疏風解毒膠囊治療兒童疾病劑量探討
[摘要] 目的 探討疏風解毒膠囊治療兒童疾病劑量。方法 選擇1～14歲兒童為研究對象，分析目前已發(fā)表文獻兒童應用疏風解毒膠囊的用藥劑量，參照中國0～18歲兒童、青少年身高、體重的標準化生長曲線計算體表面積用藥劑量、兒童體重用藥劑量，制定相應按體重用藥劑量參考值；比較文獻用藥劑量、兒童體重用藥劑量參考值與體表面積用藥劑量的誤差值。結果 所有文獻均按年齡段給藥，文獻中除1～2歲兒童劑量一致外，其他年齡段均存在2～3種用藥劑量，文獻劑量與按體表面積用藥劑量誤差值較大，兒童體重用藥劑量參考值與體表面積用藥劑量的誤差值較小。結論 推薦疏風解毒膠囊治療兒童疾病劑量：1～8歲45～50mg/kg.次，9～14歲35～40mg/kg.次。
[關鍵詞] 疏風解毒膠囊；劑量；兒童
Study on the Dose of the Shufeng Jiedu Capsule to Treat Children's Disease. Wu Qifu, The Material and Children Health Hospital, Huaying 638600, Sichuan Province, China
[Abstract] Objective To explore the dose of the treatment of children's disease with shufengjiedu capsule.Methods The children aged 1～14 years was selected as the research object. The dose of the drug is compared in the published literature. The dose were calculated according to height and weight standardized growth charts for Chinese children and adolescents aged 0～18 years,The reference dose calculated by weight and the dose calculated by body surface area were compared. Results The dose in literature were administered according to age, the children were given 2 or 3 doses except 1~2 years old. Compared with the dose calculated by body surface area, the error value is larger in literature and the error value is small in the reference dose calculated by weight. Conclusion iI is Suggested that the dose of the treatment of children's disease with shufeng jie du capsule every time according to the weight, 1-8 years of age 45～50 mg/kg, 9-14 years of age 35-40mg/kg.
[Key words] Shufeng jiedu capsule; Dose; Children